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KMID : 0984920080100020053
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Journal of Skin Barrier Research
2008 Volume.10 No. 2 p.53 ~ p.53
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Non-invasive bioengineering methods for determining dry skin in Korean women
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Baek Ji-Hwoon
Koh Jae-Sook
Lee Mi-Young
Kim Han-Jo
Kim Myoung-Rae
Kim Hyun-Jung
Lee Seung-Hun
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Abstract
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The function of skin depends on the balance between the amount of moisture in stratum corneum and the lipid layer on
the surface. The external factors such as humidity, ultraviolet rays, and temperature as well as the internal factors such as
hormone can disturb such balance in skin. Moreover, frequent use of soap and surfactant, local stimulant such as alcohol or warm water can eliminate the lipid layer on the skin surface. When the balance is upset, a condition known as dry skin is caused, which is frequently observed among patients with atopic dermatitis or chronic cutaneous disorder. Environmental factors including cold and dry weather or frequent shower can also cause dry skin. A primary factor for dry skin includes insufficient moisture in stratum corneum, epidermal hyperproliferation, abnormal lipid synthesis, impaired skin barrier, etc. These usually affect one another aggravating the symptom. Clinical symptoms include itching, scaling, tightness, and redness. The unsatisfactory and unpleasant feeling as well as constant itchiness lowers the quality of life for those who have dry skin. Physiological characteristics of the skin vary with body sites, sex, age, and race. A number of studies using noninvasive bioengineering method are currently underway. Among previous researches regarding this, Marrakchi et al. measured blood flow in various sites of body in people with normal skin in different age group. By categorizing TEWL, stratum corneum hydration, sebum content, temperature, and pH according to the body sites and ages, they clarified the causal relationship among the physiological factors. Smalls et al. reported that the quantitative measurement of physiological factors of the skin using non-invasive methods is very effective in investigating the physiological changes in the structure of skin and its functions. Fischer et al. described the methods available for the assessment of dry skin. In this study, we conducted a self-evaluation, a clinical examination of the facial skin and non-invasive measurements for Korean women. The purpose of this study was to find the most useful parameters for classification of dry skin based on a clinical assessment and to suggest the reference values for categorizing dry skin in Korean women. In conclusion, the questionnaire survey found that 72% of the respondents had dry skin. Clinical assessment focusing on the cheek for skin roughness and scaling resulted in 6 subjects had very dry skin(5.83%), 29 had dry skin(28.15%), and 68 had normal skin with sufficient moisture(66.02%). We determined the values for categorization of dry skin using skin capacitance(r = 0.550, p < 0.01), dielectric constant(r = 0.227, p < 0.05), TEWL(r = -0.217, p < 0.05), R5(r = 0.320, p < 0.01) and R7(r = 0.341, p < 0.01) parameters for mechanical property, and scaling(r = -0.437, p < 0.01) which had relatively higher correlations with clinical assessment than other parameters. Using the classifications by clinical
assessment‘, Very dry’‘, Dry’and‘ Nomal’, we obtained the reference values of each parameter for categorizing dry skin.
Our study provided general information about the physiological characteristics of normal skin in Korean women and suggested the reference values for categorizing dry skin.
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KEYWORD
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korean women, dry skin, non-invasive bioengineering methods
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